Immunosuppressive agents for treating IgA nephropathy
نویسندگان
چکیده
منابع مشابه
Treating IgA nephropathy.
IgA nephropathy may be the most common type of glomerulonephritis, worldwide. Once thought benign, it causes endstage renal disease in 15 to 20% of individuals within 10 yr of onset (1) and in 30 to 35% of individuals within 20 yr of onset. Proteinuria, an elevated serum creatinine concentration, and hypertension predict progression (1) as does a renal biopsy demonstrating focal proliferative g...
متن کامل[Immunosuppressive and non-immunosuppressive agents for patients with IgA nephropathy: guideline from the Italian Society of Nephrology].
BACKGROUND The current 3rd edition of the Italian Society of Nephrology guidelines has been drawn up to summarize evidence of key intervention issues on the basis of systematic reviews (SR) of randomized trials (RCT) or RCT data only. In the present guideline, evidence of the use of immunosuppressive and non-immunosuppressive treatments in IgA nephropathy (IgAN) is presented. METHODS SR of RC...
متن کاملImmunosuppressive agents versus steroids in the treatment of IgA nephropathy-induced proteinuria: A meta-analysis
Immunoglobulin A nephropathy (IgAN) is one of the most common types of primary glomerular disease. Immunosuppressive treatment for patients with IgAN remains controversial. The present meta-analysis aimed to assess the efficacy and safety of various immunosuppressive agents compared with steroids in patients with IgAN and moderate to severe proteinuria. PubMed, EMBASE, Cochrane Library, Chinese...
متن کاملClinical Course of Patients with IgA Nephropathy between Combined Treatment of Immunosuppressive Agents and ACE Inhibitor and ACE Inhibitor alone
BACKGROUND It has not been clear whether immunosuppressive therapy favorably influences renal function and proteinuria in IgA nephropathy (IgAN). Angiotensin converting enzyme inhibitor (ACEi) has an anti-proteinuric effect in IgAN. A retrospective study was done to see whether the addition of immunosuppressive therapy to ACEi produces a more excellent anti-proteinuric effect and preserves bett...
متن کاملIgA nephropathy.
A great interest in IgA nephropathy was demonstrated in the last few years. Unfortunately, a complete picture of this chronic disease should not yet been made. The article deals with 7 patients with IgA nephropathy treated in our Institute. The following characteristics were examined during a long period of time (1-17 years): clinical picture, course of the disease, clinical and morphologic cor...
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ژورنال
عنوان ژورنال: Cochrane Database of Systematic Reviews
سال: 2020
ISSN: 1465-1858
DOI: 10.1002/14651858.cd003965.pub3